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Details on Person Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation

Class:Id	BlackBoxEvent:109342
_displayName	Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation
_doRelease	TRUE
_timestamp	2016-11-10 00:57:06
authored	[InstanceEdit:109689] Gillespie, ME, 2004-01-19 00:00:00
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:109340] Gillespie, ME, 2004-01-02 00:00:00
figure	[Figure:109987] /figures/unsatfattyacidbetao_3.jpg
goBiologicalProcess	[GO_BiologicalProcess:20426] fatty acid beta-oxidation
input	[SimpleEntity:77360] trans,cis-Lauro-2,6-dienoyl-CoA [mitochondrial matrix] [SimpleEntity:113596] FAD [mitochondrial matrix] [SimpleEntity:113521] H2O [mitochondrial matrix] [SimpleEntity:113526] NAD+ [mitochondrial matrix] [SimpleEntity:29374] CoA-SH [mitochondrial matrix]
literatureReference	[Book:77402] The Metabolic and Molecular Bases of Inherited Disease, 8th ed Scriver, CR Mitochondrial fatty acid oxidation disorders 0079130356
modified	[InstanceEdit:109689] Gillespie, ME, 2004-01-19 00:00:00 [InstanceEdit:110059] Gillespie, ME, 2004-01-23 15:21:05 [InstanceEdit:111217] Gillespie, ME, 2004-02-10 11:51:38 [InstanceEdit:163376] Vastrik, I, 2005-04-29 06:26:51 [InstanceEdit:194432] Schmidt, EE, 2007-03-13 12:36:16 [InstanceEdit:5422851] D'Eustachio, Peter, 2014-05-05 [InstanceEdit:8946993] Shorser, Solomon, 2016-11-07 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation Removal of 2 Carbon atoms from trans,cis-Lauro-2,6-dienoyl-CoA to form 4-cis-decenoyl-CoA
output	[SimpleEntity:109986] 4-cis-decenoyl-CoA [mitochondrial matrix] [SimpleEntity:31649] FADH2 [mitochondrial matrix] [SimpleEntity:29362] NADH [mitochondrial matrix] [SimpleEntity:113559] Ac-CoA [mitochondrial matrix] [SimpleEntity:113529] H+ [mitochondrial matrix]
precedingEvent	[Reaction:109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA [Homo sapiens] [BlackBoxEvent:109339] Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation [Homo sapiens]
regulatedBy	[Requirement:5422854] Requirement by 'Trifunctional Protein [mitochondrial matrix]' [Requirement:5422856] Requirement by 'ACADL tetramer [mitochondrial matrix]'
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361036] R-HSA-109342.4
summation	[Summation:109988] One cycle of beta oxidation, each mediated by the activities...
(hasEvent)	[Pathway:77288] mitochondrial fatty acid beta-oxidation of unsaturated fatty acids [Homo sapiens]
(precedingEvent)	[Reaction:109341] dehydrogenation of 4-cis-decenoyl-CoA to form 2-trans-4-cis-decadienoyl-CoA [Homo sapiens] [Reaction:163217] Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9786554] Update Tracker - [BlackBoxEvent:109342] Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation - v49:[addRegulator, modifyText, removeCatalystActivity]
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