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Details on Person UniProt:Q9V719 Sin1
Class:Id
ReferenceGeneProduct:104993
_chainChangeLog
chain:1-569 added on Sat February 7 2015
_displayName
UniProt:Q9V719 Sin1
_timestamp
2025-02-21 19:22:54
chain
chain:1-569
checksum
BD18DC6186C4E665
comment
FUNCTION Component of the target of rapamycin complex 2 (TORC2), which transduces signals from growth factors to pathways involved in proliferation, cytoskeletal organization and anabolic output (PubMed:16919458, PubMed:17043309). In response to growth factors, TORC2 phosphorylates and activates AGC protein kinase family members, such as Akt1 (PubMed:16919458, PubMed:17043309). Within the TORC2 complex, Sin1 acts as a substrate adapter which recognizes and binds AGC protein kinase family members for phosphorylation by mTor (By similarity).SUBUNIT Component of the target of rapamycin complex 2 (TORC2).SIMILARITY Belongs to the SIN1 family.
description
recommendedName: Stress-activated map kinase-interacting protein 1 shortName: SAPK-interacting protein 1 shortName: dSin1
