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Details on Person UniProt:P22726 Wnt5b
Class:Id
ReferenceGeneProduct:104900
_chainChangeLog
signal peptide:1-17 added on Fri February 6 2015;chain:18-359 added on Fri February 6 2015
_displayName
UniProt:P22726 Wnt5b
_timestamp
2023-11-03 18:20:26
chain
signal peptide:1-17 chain:18-359
checksum
308ED393D3020DEB
comment
FUNCTION Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters.SUBUNIT Interacts with PORCN.SUBCELLULAR LOCATION Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.SIMILARITY Belongs to the Wnt family.
description
recommendedName: Protein Wnt-5b
geneName
Wnt5b Wnt-5b
identifier
P22726
isSequenceChanged
FALSE
keyword
Developmental protein Disulfide bond Extracellular matrix Glycoprotein Lipoprotein Reference proteome Secreted Signal Wnt signaling pathway
