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Details on Person UniProt:P59534 TAS2R39

Class:IdReferenceGeneProduct:103728
_chainChangeLogchain:1-338 added on Fri February 6 2015
_displayNameUniProt:P59534 TAS2R39
_timestamp2023-11-03 15:22:34
chainchain:1-338
checksumF9CD1860008198AB
commentFUNCTION Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).SUBCELLULAR LOCATION Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.MISCELLANEOUS Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.SIMILARITY Belongs to the G-protein coupled receptor T2R family.
descriptionrecommendedName: Taste receptor type 2 member 39 shortName: T2R39 alternativeName: Taste receptor type 2 member 57 shortName: T2R57
geneNameTAS2R39
identifierP59534
isSequenceChangedFALSE
keywordG-protein coupled receptor
Glycoprotein
Membrane
Receptor
Reference proteome
Sensory transduction
Taste
Transducer
Transmembrane
Transmembrane helix
modified[InstanceEdit:9836292] Weiser, Joel, 2023-05-25
[InstanceEdit:9852000] Weiser, Joel, 2023-11-03
nameTAS2R39
referenceDatabase[ReferenceDatabase:2] UniProt
referenceGene[ReferenceDNASequence:8995728] ENSEMBL:ENSG00000236398 TAS2R39 [Homo sapiens]
secondaryIdentifierT2R39_HUMAN
A4FUI7
Q3ZCN6
Q645W4
sequenceLength338
species[Species:48887] Homo sapiens
(referenceEntity)[EntityWithAccessionedSequence:3299609] TAS2R39 [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by UniProt:P59534 TAS2R39 (103728)