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Details on Person UniProt:Q60846 Tnfrsf8
Class:Id
ReferenceGeneProduct:103609
_chainChangeLog
signal peptide:1-18 added on Fri February 6 2015;chain:19-498 added on Fri February 6 2015
_displayName
UniProt:Q60846 Tnfrsf8
_timestamp
2023-11-03 17:35:27
chain
signal peptide:1-18 chain:19-498
checksum
98CA2A05B38AFA71
comment
FUNCTION Receptor for TNFSF8/CD30L (PubMed:8543792). May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).SUBUNIT Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.SUBCELLULAR LOCATION Detected in thymus and in activated splenocytes.INDUCTION By concanavalin A and pokeweed mitogen in splenocytes.SIMILARITY Belongs to the TNFR8 family.
