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Details on Person UniProt:Q9QYH9 Tnfsf14
| Class:Id | ReferenceGeneProduct:103574 |
|---|---|
| _chainChangeLog | chain:1-239 added on Sat February 7 2015;chain:-239 added on Sat February 7 2015 |
| _displayName | UniProt:Q9QYH9 Tnfsf14 |
| _timestamp | 2023-11-03 17:09:17 |
| chain | chain:1-239 chain:82-239 |
| checksum | 217874AC71AD6BE3 |
| comment | FUNCTION Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (By similarity).SUBUNIT Homotrimer. Interacts with TNFRSF14.SUBCELLULAR LOCATION The soluble form derives from the membrane form by proteolytic processing.SIMILARITY Belongs to the tumor necrosis factor family. |
| description | recommendedName: Tumor necrosis factor ligand superfamily member 14 cdAntigenNameCD258/cdAntigenName component recommendedName: Tumor necrosis factor ligand superfamily member 14, membrane form /component component recommendedName: Tumor necrosis factor ligand superfamily member 14, soluble form /component |
| geneName | Tnfsf14 Light |
| identifier | Q9QYH9 |
| isSequenceChanged | FALSE |
| keyword | Cell membrane Cytokine Disulfide bond Glycoprotein Membrane Reference proteome Secreted Signal-anchor Transmembrane Transmembrane helix |
| modified | [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10 [InstanceEdit:217385] Schmidt, EE, 2008-03-27 06:23:53 [InstanceEdit:354386] Schmidt, EE, 2008-06-18 04:45:12 [InstanceEdit:384350] Kanapin, AA, 2008-11-26 14:00:39 [InstanceEdit:392885] Kanapin, AA, 2009-03-09 12:07:18 [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35 [InstanceEdit:423310] Kanapin, AA [InstanceEdit:435478] Kanapin, AA [InstanceEdit:435871] Kanapin, AA [InstanceEdit:447347] Kanapin, AA [InstanceEdit:525883] Kanapin, AA [InstanceEdit:613449] Kanapin, AA [InstanceEdit:797602] Kanapin, AA [InstanceEdit:937368] Yung, CK [InstanceEdit:1042053] Yung, CK [InstanceEdit:1220657] Yung, CK [InstanceEdit:1300696] Yung, CK [InstanceEdit:1301627] Yung, CK [InstanceEdit:1551960] Weiser, JD [InstanceEdit:1995863] Weiser, JD [InstanceEdit:2132304] Weiser, JD [InstanceEdit:2265580] Weiser, JD [InstanceEdit:5433710] Weiser, JD [InstanceEdit:5618415] Weiser, JD [InstanceEdit:5634237] Weiser, JD [InstanceEdit:5673015] Weiser, JD [InstanceEdit:9037114] Weiser, JD [InstanceEdit:9616384] Weiser, JD [InstanceEdit:9637257] Weiser, JD [InstanceEdit:9657908] Weiser, JD [InstanceEdit:9676415] Weiser, JD [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 |
| name | Tnfsf14 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| secondaryIdentifier | TNF14_MOUSE Q059Y9 |
| sequenceLength | 239 |
| species | [Species:48892] Mus musculus |
| (referenceEntity) | [EntityWithAccessionedSequence:5668781] Tnfsf14 [plasma membrane] [Mus musculus] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by UniProt:Q9QYH9 Tnfsf14 (103574)
