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Details on Person CREBBP,EP300 [nucleoplasm]

Class:IdDefinedSet:1027362
_displayNameCREBBP,EP300 [nucleoplasm]
_timestamp2018-10-01 14:46:53
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:1027366] Garapati, P V, 2010-11-17
hasMember
modified[InstanceEdit:8983918] Jupe, Steve, 2017-03-31
[InstanceEdit:9622578] Orlic-Milacic, Marija, 2018-10-01
nameCREBBP,EP300
CBP/p300
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:1107840] R-HSA-1027362.3
(activeUnit)[CatalystActivity:5660659] acetyltransferase activity of NFKB1:p-S276-RELA:p300/CBP [nucleoplasm]
[CatalystActivity:9617754] protein-lysine-acetyltransferase activity of CREBPP-S-S-FOXO4:FOXO4-S-S-CREBBP,EP300-S-S-FOXO4:FOXO4-S-S-EP300 [nucleoplasm]
[CatalystActivity:9760084] protein N-acetyltransferase activity of p-NFE2L2:CREBBP,EP300 [nucleoplasm]
[CatalystActivity:9926428] histone acetyltransferase activity of MITF-M:CREBBP,EP300 [nucleoplasm]
[CatalystActivity:9984956] histone H3K27 acetyltransferase activity of ORF50 gene:H3K4me3,H3K27me3-Nucleosome:SIRT1:HIF:CREBBP,EP300 [nucleoplasm]
[PositiveGeneExpressionRegulation:9622623] Positive gene expression regulation by 'FOXO1,FOXO3,(FOXO4):NF-Y:CREBBP,EP300:BCL2L11 gene [nucleoplasm]'
(hasComponent)[Complex:933471] CBP/p300:pIRF7:pIRF7 [nucleoplasm] [Homo sapiens]
[Complex:1027360] VAF (virus-activated factor) [nucleoplasm] [Homo sapiens]
[Complex:1027364] p-T,4S-IRF3:p-T,4S-IRF3:CREBBP, EP300 [nucleoplasm] [Homo sapiens]
[Complex:3134898] beta-catenin:IRF3:p300 [nucleoplasm] [Homo sapiens]
[Complex:3322396] TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] [Homo sapiens]
[Complex:5660656] NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] [Homo sapiens]
[Complex:5660657] NFKB1:p-S276,5AcK-RELA:p300/CBP [nucleoplasm] [Homo sapiens]
[Complex:9622566] NF-Y:CREBBP,EP300:BCL2L11 gene [nucleoplasm] [Homo sapiens]
[Complex:9760062] p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm] [Homo sapiens]
[Complex:9760065] p-NFE2L2:CREBBP,EP300 [nucleoplasm] [Homo sapiens]
List all 91 refering instances
(input)[Reaction:933536] p-IRF7 dimer interacts with coactivator CBP/p300 [Homo sapiens]
[Reaction:1028817] CREBBP, EP300 binds p-T,4S-IRF3:p-T,4S-IRF3 [Homo sapiens]
[Reaction:1028820] Formation of VAF (virus-activated factor) complex [Homo sapiens]
[Reaction:3134883] Beta-catenin enhances association of IRF3 with CBP/p300 [Homo sapiens]
[Reaction:3322427] Beta-catenin recruits CBP/p300 [Homo sapiens]
[Reaction:5660666] CBP and p300 binds NF-kB complex [Homo sapiens]
[Reaction:9617683] EP300,CREBBP bind SOH-C481-FOXO4 [Homo sapiens]
[Reaction:9622572] NF-Y and CREBBP,EP300 constitutively bind BCL2L11 gene promoter [Homo sapiens]
[Reaction:9760082] NFE2L2 binds CREBBP,EP300 [Homo sapiens]
[BlackBoxEvent:9843120] Coactivators are recruited to liganded PPARG:RXRA heterodimer [Homo sapiens]
List all 12 refering instances
(output)[Reaction:9617758] EP300,CREBBP acetylate FOXO4 [Homo sapiens]
(physicalEntity)[CatalystActivity:5083648] protein N-acetyltransferase activity of CREBBP,EP300 [nucleoplasm]
(updatedInstance)[_UpdateTracker:9897026] Update Tracker - [DefinedSet:1027362] CREBBP,EP300 [nucleoplasm] - v61:[addName]
[_UpdateTracker:9899769] Update Tracker - [DefinedSet:1027362] CREBBP,EP300 [nucleoplasm] - v67:[modifyName]
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No pathways have been reviewed or authored by CREBBP,EP300 [nucleoplasm] (1027362)
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