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Details on Person UniProt:Q9BRJ2 MRPL45
| Class:Id | ReferenceGeneProduct:100337 |
|---|---|
| _chainChangeLog | transit peptide:1- added on Fri February 6 2015;chain:-306 added on Fri February 6 2015 |
| _displayName | UniProt:Q9BRJ2 MRPL45 |
| _timestamp | 2024-11-03 19:48:18 |
| chain | transit peptide:1- chain:-306 |
| checksum | C00CC379D337910A |
| comment | FUNCTION Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:33602856, PubMed:35177605). Within the mitochondrial ribosomes, required to direct the nascent polypeptide toward the tunnel exit and position the exit at a distance from the membrane surface (PubMed:33602856).SUBUNIT Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:25278503, PubMed:25838379, PubMed:28892042, PubMed:33243891, PubMed:33602856). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit (PubMed:25278503, PubMed:25838379, PubMed:28892042). The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins (PubMed:25278503, PubMed:25838379, PubMed:28892042). The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins (PubMed:25278503, PubMed:25838379, PubMed:28892042).INTERACTION Belongs to the mitochondrion-specific ribosomal protein mL45 family. |
| description | recommendedName: fullName evidence="9"Large ribosomal subunit protein mL45 alternativeName: 39S ribosomal protein L45, mitochondrial shortName: L45mt shortName: MRP-L45 |
| geneName | MRPL45 |
| identifier | Q9BRJ2 |
| isSequenceChanged | FALSE |
| keyword | 3D-structure Mitochondrion Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide |
| modified | [InstanceEdit:9836292] Weiser, Joel, 2023-05-25 [InstanceEdit:9841277] Weiser, Joel [InstanceEdit:9852000] Weiser, Joel, 2023-11-03 [InstanceEdit:9917590] Weiser, Joel, 2024-08-09 [InstanceEdit:9926675] Weiser, Joel, 2024-11-03 |
| name | MRPL45 |
| referenceDatabase | [ReferenceDatabase:2] UniProt |
| referenceGene | [ReferenceDNASequence:8988628] ENSEMBL:ENSG00000277936 MRPL45 [Homo sapiens] |
| secondaryIdentifier | RM45_HUMAN A1L436 Q6ZMJ5 |
| sequenceLength | 306 |
| species | [Species:48887] Homo sapiens |
| (referenceEntity) | [EntityWithAccessionedSequence:5368224] MRPL45 [mitochondrial inner membrane] [Homo sapiens] |
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No pathways have been reviewed or authored by UniProt:Q9BRJ2 MRPL45 (100337)
